Insights into the role that inflammatory mediators such as lymphocytes and matrix metalloproteinases play in remodeling of the basement membranes of salivary gland cells in patients with Sjögren’s syndrome has led to several observations revealing irregular thickening and thinning of the basement membrane. These observations have revealed that the underlying mechanism for these irregularities in thickness may partly be due to laminin degradation in the basement membrane seen coincidentally along with the intracellular accumulation of laminin in salivary gland ductal and acinar cells.
Mohammad M Pour, Charles M Cobb and Carole P McArthur
All Published work is licensed under a Creative Commons Attribution 4.0 International License
Copyright © 2018 All rights reserved. iMedPub LTD Last revised : October 18, 2018